In recent decades, scholars’ and practitioners’ interest in star performers and high-potential employees (HiPos) has increased dramatically. To date, however, researchers have considered these two classifications of exceptional talent in relative isolation of one another, despite the fact that they are widely considered to comprise organizations’ most valuable employees. The current article identifies and explores key intersections in the heretofore-siloed streams of research on star employees and HiPos. In so doing, we identify core assumptions, highlight questions that emerge at focal intersections, and offer a foundation for the cross-fertilization of insights to strengthen the scholarly and practical impact of inquiry related to both groups. We then consider the implications of four significant recent trends in the world of work – increased employee mobility; greater focus on issues related to diversity, equity, and inclusion in the workplace; cross-cultural issues; and the broader set of technological changes that are shaping the workplace – for research and practice related to stars and HiPos. Along the way, we highlight the integral and path-breaking contributions of publications in Personnel Psychology to our knowledge about organizations’ best talent.