We performed a modeling study of the potential impacts of alternative transit-oriented urban design scenarios on community exposures to roadway air pollution. Specifically, we used a modeling framework developed previously for the study area that includes activity-based travel demand modeling (Tampa ABM), a dynamic traffic assignment model (MATSim), a mobile-source emissions model (MOVES), a line-source dispersion model (RLINE), and a population exposure model. Data from the 2040 transit plan envisioned by the Tampa Bay Area Regional Transportation Authority were added to the modeling system along with scenarios for reassignment of household residence locations to parcels near to both employment centers and transit stops. Results of modeling simulations on predicted daily activity-travel patterns, shifts in measures of travel, link-specific diurnally-varying roadway emissions, spatiotemporal distributions of concentrations, and population distributions of exposures to oxides of nitrogen were assessed to compare potential design and transport policy choices.