Kidney Transportation: Improving Success Rates of Transportation for Transplanting Organs
| dc.contributor.author | O'Brien, Ariana | |
| dc.contributor.author | Patel, Rhianna | |
| dc.contributor.author | Rougeuz, Cody | |
| dc.date.accessioned | 2024-05-17T14:18:32Z | |
| dc.date.available | 2024-05-17T14:18:32Z | |
| dc.date.issued | 2024-05-17 | |
| dc.description.abstract | With only 4% of people with kidney failure receiving a transplant in the US due to miscommunication in the supply chain, delayed time spent in transportation, and damage during transportation, there is a substantial need to improve the transportation of the donation system. Using a finite element analysis, cooling during organ transportation can be modeled to fully understand heat transfer between the transportation system and the organ. Here, we used conductive heat transfer and melting physics in a 3D model of a transportation module designed for a kidney. The kidney is contained in an insulated environment with a frozen saline solution-based cooling mechanism to develop a novel understanding of the crucial parameters involved in temperature fluctuations and the time elapsed before the organ reaches a threshold temperature that makes it no longer viable for transplantation. We determined the optimized parameters for the transportation vessel and cooling mechanism while considering external environmental temperatures. Our findings suggest that using an insulating material made of polyurethane, with a cooling mechanism involving Easislush, starting at an initial temperature of -4℃, ensures the optimal conditions to keep a kidney viable for transplantation over 36 hours. | |
| dc.identifier.uri | https://hdl.handle.net/1813/115205 | |
| dc.language.iso | en_US | |
| dc.rights | Attribution 4.0 International | en |
| dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | |
| dc.subject | COMSOL Multiphysics | |
| dc.subject | Kidney | |
| dc.subject | Organ Transportation Vessel | |
| dc.subject | Conductive Heat Transfer | |
| dc.subject | Design Optimization | |
| dc.title | Kidney Transportation: Improving Success Rates of Transportation for Transplanting Organs | |
| dc.type | report |
Files
Original bundle
1 - 1 of 1