Trimethylamine N-oxide in Humans and Dairy Cows: Should We Be Concerned?
McFadden, J.W.; Myers, W.A.
The gastrointestinal degradation of choline, betaine, and carnitine results in the formation of trimethylamine N-oxide (TMAO) in humans and dairy cows. In humans, TMAO has emerged as an associative biomarker for non-alcoholic fatty liver disease, cardiovascular disease, and type 2 diabetes; however, conflicting data is emerging. This presentation will explore the role of TMAO, the effect of diet on the gut microbiome in relation to TMAO formation, and new work focused on the effects or lack thereof in dairy cows.
Presented at 2020 Virtual Cornell Nutrition Conference
Department of Animal Science
Choline; Dairy; Human health; Trimethylamine N-oxide
conference papers and proceedings