Professor Searle is Chair of the Department of Ecology and Evolutionary Biology at Cornell University, and is interested in the construction of post-glacial small mammal communities and has studied the natural colonization history of European shrews, voles, mice and small carnivores, revealing a wide range of species- and lineage-specific responses in terms of source areas and pattern of spread. Unnatural colonization history (i.e. transport by humans) is also of interest to him, particularly the way that the phylogeography of small mammals transported by humans can inform about the history of the humans moving them.

Those separate lineages that make up a species and which are formed in different places and colonize in different ways, are genetically differentiated to various degrees and may become separate species themselves. He is interested in the speciation process and the analysis of hybrid zones to inform about that. He has, in particular, studied the origin of chromosomally distinctive lineages, and the hybrid zones between those lineages, using shrews and mice as models.

A more complete and current listing of Prof. Searle's work and scholarly output can be found on his EEB Department web page and the Searle Lab web site, or through the links below.

ResearchGate Profile Page


Recent Submissions

  • The Changing pace of Insular Life: 5000 Years of Microevolution in the Orkney Vole (microtus Arvalis Orcadensis) 

    Cucchi, T.; Barnett, R.; Martínková, N.; Renaud, S.; Renvoisé, E.; Evin, A.; Sheridan, A.; Mainland, I.; Wickham?Jones, C.; Tougard, C.; Quéré, J.P.; Pascal, M.; Pascal, M.; Heckel, G.; O'Higgins, P.; Searle, J.B.; Dobney, K.M. (Society for the Study of Evolution, 2014-06-23)
    Island evolution may be expected to involve fast initial morphological divergence followed by stasis. We tested this model using the dental phenotype of modern and ancient common voles (Microtus arvalis), introduced onto ...
  • The hypothetical Old-Northern chromosome race of Sorex araneus found in the Ural Mts 

    Polyakov, A.V.; Borodin, P.M.; Luká?ová, L.; Searle, J.B.; Zima, J. (Finnish Zoological and Botanical Publishing Board, 1997)
    Chromosomes of two populations of the common shrew, Sorex araneus L. (Mammalia, Insectivora, Soricidae), from the northern Ural Mts. were investigated. In both sites, homozygous, all-metacentric autosomal complements were ...
  • Synchronous diversification of Sulawesi’s iconic artiodactyls driven by recent geological events 

    Frantz, Laurent A. F.; Rudzinski, Anna; Nugraha, Abang Mansyursyah Surya; Evin, Allowen; Burton, James; Hulme-Beaman, Ardern; Linderholm, Anna; Barnett, Ross; Vega, Rodrigo; Irving-Pease, Evan K.; Haile, James; Allen, Richard; Leus, Kristin; Shephard, Jill; Hillyer, Mia; Gillemot, Sarah; van den Hurk, Jeroen; Ogle, Sharron; Atofanei, Cristina; Thomas, Mark G.; Johansson, Friederike; Mustari, Abdul Haris; Williams, John; Mohamad, Kusdiantoro; Damayanti, Chandramaya Siska; Wiryadi, Ita Djuwita; Obbles, Dagmar; Mona, Stephano; Day, Hally; Yasin, Muhammad; Meker, Stefan; McGuire, Jimmy A.; Evans, Ben J.; von Rintelen, Thomas; Ho, Simon Y. W.; Searle, J. B.; Kitchener, Andrew C.; Macdonald, Alastair A.; Shaw, Darren J.; Hall, Robert; Galbusera, Peter; Larson, Greger (The Royal Society, 2018-04-11)
    The high degree of endemism on Sulawesi has previously been suggested to have vicariant origins, dating back to 40 Ma. Recent studies, however, suggest that much of Sulawesi's fauna assembled over the last 15 Myr. Here, ...
  • R2d2 Drives Selfish Sweeps in the House Mouse 

    Didion, John P.; Morgan, Andrew P.; Yadgary, Liran; Bell, Timothy A.; McMullan, Rachel C.; Ortiz de Solorzano, Lydia; Britton-Davidian, Janice; Bult, Carol J.; Campbell, Karl J.; Castiglia, Riccardo; Ching, Yung-Hao; Chunco, Amanda J.; Crowley, James J.; Chesler, Elissa J.; Förster, Daniel W.; French, John E.; Gabriel, Sofia I.; Gatti, Daniel M.; Garland, Theodore; Giagia-Athanasopoulou, Eva B.; Giménez, Mabel D.; Grize, Sofia A.; Gündüz, ?slam; Holmes, Andrew; Hauffe, Heidi C.; Herman, Jeremy S.; Holt, James M.; Hua, Kunjie; Jolley, Wesley J.; Lindholm, Anna K.; López-Fuster, María J.; Mitsainas, George; da Luz Mathias, Maria; McMillan, Leonard; da Graça Morgado Ramalhinho, Maria; Rehermann, Barbara; Rosshart, Stephan P.; Searle, J. B.; Shiao, Meng-Shin; Solano, Emanuela; Svenson, Karen L.; Thomas-Laemont, Patricia; Threadgill, David W.; Ventura, Jacint; Weinstock, George M.; Pomp, Daniel; Churchill, Gary A.; Pardo-Manuel de Villena, Fernando (Oxford University Press on behalf of the Society for Molecular Biology and Evolution, 2016-02-15)
    A selective sweep is the result of strong positive selection driving newly occurring or standing genetic variants to fixation, and can dramatically alter the pattern and distribution of allelic diversity in a population. ...
  • Staggered chromosomal hybrid zones in the house mouse: relevance to reticulate evolution and speciation 

    Gündüz, ?.; Pollock, C.L.; Giménez, M.D.; Förster, D.W.; White, T.A.; Sans-Fuentes, M.A.; Hauffe, H.C.; Ventura, J.; López-Fuster, M.J.; Searle, J.B. (Multidisciplinary Digital Publishing Insitute (MDPI), 2010-09)
    In the house mouse there are numerous chromosomal races distinguished by different combinations of metacentric chromosomes. These may come into contact with each other and with the ancestral all-acrocentric race, and form ...
  • Playing Hide-and-Seek in Beta-Globin Genes: Gene Conversion Transferring a Beneficial Mutation between Differentially Expressed Gene Duplicates 

    Strážnická, Michaela; Marková, Silvia; Searle, J. B.; Kotlík, Petr (Multidisciplinary Digital Publishing Institute (MDPI), 2018-10-12)
    Increasing evidence suggests that adaptation to diverse environments often involves selection on existing variation rather than new mutations. A previous study identified a nonsynonymous single nucleotide polymorphism (SNP) ...
  • Reconstructing Asian faunal introductions to eastern Africa from multi-proxy biomolecular and archaeological datasets 

    Prendergast, M.E.; Buckley, M.; Crowther, A.; Eager, H.; Frantz, L.; Lebrasseur, O.; Hutterer, R.; Hulme-Beaman, A.; Van Neer, W.; Douka, K.; Veall, M.-A.; Quintana Morales, E.M.; Schuenemann, V.J.; Reiter, E.; Allen, R.; Helm, R.; Shipton, C.; Mwebi, O.; Denys, C.; Horton, M.; Wynne-Jones, S.; Fleisher, J.; Radimilahy, C.; Wright, H.; Searle, J.B.; Krause, J.; Larson, G.; Boivin, N.L. (Public Library of Science, 2017-08)
    Human-mediated biological exchange has had global social and ecological impacts. In sub-Saharan Africa, several domestic and commensal animals were introduced from Asia in the pre-modern period; however, the timing and ...
  • Over a Thousand Years of Evolutionary History of Domestic Geese from Russian Archaeological Sites, Analysed Using Ancient DNA 

    Honka, J.; Heino, M.T.; Kvist, L.; Askeyev, I.V.; Shaymuratova, D.N.; Askeyev, O.V.; Askeyev, A.O.; Heikkinen, M.E.; Searle, J.B.; Aspi, J. (Multidisciplinary Digital Publishing Institute (MDPI), 2018-07-20)
    The European domestic goose is a widely farmed species known to have descended from the wild greylag goose (Anser anser). However, the evolutionary history of this domesticate is still poorly known. Ancient DNA studies ...
  • Dual mechanism of chromatin remodeling in the common shrew sex trivalent (XY1Y2) 

    Matveevsky, S.N.; Pavlova, S.V.; Atsaeva, M.M.; Searle, J.B.; Kolomiets, O.L. (Pensoft Publishers, 2017-11-03)
    Here we focus on the XY1Y2 condition in male common shrew Sorex araneus Linnaeus, 1758, applying electron microscopy and immunocytochemistry for a comprehensive analysis of structure, synapsis and behaviour of the sex ...
  • Enhancing diversity in undergraduate science: self-efficacy drives performance gains with active learning 

    Ballen, C.J.; Wieman, C.; Salehi, S.; Searle, J.B.; Zamudio, K.R. (American Society for Cell Biology, 2017-12-01)
    Efforts to retain underrepresented minority (URM) students in science, technology, engineering, and mathematics (STEM) have shown only limited success in higher education, due in part to a persistent achievement gap between ...

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