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BEE 4530 - 2016 Student Papers
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Optimization of Contact Lens Drug Delivery to Ocular Tissue
(2016-05-16)Intraocular pressure is a risk factor for developing glaucoma, a disease that damages the optic nerve and can result in vision impairment. Timolol is a beta-adrenergic antagonist that decreases intraocular pressure (IOP) ... -
Procoagulant Microparticle Interactions Due to P-sel-Ig in Hemophilia A Patients
(2016-05-16)Congenital hemophilia is a hereditary, X-linked blood-clotting disease that involves insufficient clotting factors VIII and IX. There are two types of hemophilia, Hemophilia A and Hemophilia B. Hemophilia A is the most ... -
Finite Element Modeling of Thermal Regulation in Extra Vehicular Activity
(2016-05-16)Astronauts perspire heavily during the strenuous exercise of Extravehicular Activity (EVA), and previous literature has expressed concern that this may negatively impact the ability of the LCVG to maintain thermal comfort. ... -
Cupric Ion Release from Various IUD Geometries
(2016-05-16)Intrauterine Devices (IUDs) are gaining popularity as a form of long-acting reversible contraceptives (LARC); once inserted, copper IUDs can be effective for up to ten years and require no action from the user. The ... -
Endovenous Laser Treatment for Occlusion of Varicose Veins
(2016-05-16)Endovenous laser treatment (ELT) is a minimally invasive technique that uses laser energy to treat varicose veins. An optical fiber is inserted under the guidance of ultrasound and laser light is shone into the interior ... -
Breaking the Skin Barrier: Modelling Microneedles for Transdermal Insulin Delivery
(2016-05-16)Transdermal patches, devices developed to deliver drugs, can be limited in their efficacy because the amount of drug that diffuses through the skin often doesn’t reach sufficient concentrations. This problem is alleviated ... -
A Computer Model for Evaluating the Efficiency of Cryosurgery for Prostate Cancer
(2016-05-16)We model the effects of the cryosurgery process for prostate cancer in COMSOL Multiphysics® (ver 5.1) using imaging and manufacturing data to generate 3D realistic geometry for the prostate and cryoprobe. By imposing a ... -
Modeling Carmustine Diffusion from Gliadel® Wafers in the Brain to Optimize Cancer Treatment and Minimize Damage to Healthy Tissue
(2016-05-16)Gliadel® wafers have been developed to circumvent traditional obstacles in brain cancer treatment. Chemotherapeutic drugs administered intravenously are rendered largely ineffective by the blood-brain barrier. Gliadel ... -
Drug Delivery from PLGA-Coated Stents: Optimization of Strut Geometry and Extent of Embedment in the Arterial Wall
(2016-05-16)Patients with atherosclerosis experience plaque buildup in the coronary artery, reducing blood flow and increasing the likelihood of a blood clot. Balloon angioplasty and the implantation of a metal stent are physical ... -
Modeling the Cornea During Laser Ablation Procedures
(2016-05-16)Photorefractive keratectomy (PRK) is a form of laser eye surgery used to correct vision. This procedure entails the precise removal of corneal tissue by laser ablation. It has been shown experimentally that dehydration of ...
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