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Browsing Biological Sciences Honors Theses by Title
Now showing items 14-33 of 40
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Exploring the functional role of the bacterial protein SeqA and co--?occurring genome stability systems in TnsE--?mediated Tn7 transposition using the E. coli model system
(2013-05)Transposon Tn7, is unique among transposons for both its target specificity and selectivity. One of its target selection pathways, mediated by the protein TnsE, has been found to allow Tn7 to preferentially transpose into ... -
Exploring the role of differential gene expression in the age-associated impairment of peripheral nerve regeneration
(2020-06)The peripheral nervous system’s ability to regenerate after injury declines with age, but the reason for why this occurs is unknown. With the goal to understand the role of age-associated transcriptional changes in the ... -
Genetic Basis of Rotenone-induced Parkinson’s Disease Model in Drosophila melanogaster
(2020-06)Parkinson’s disease (PD) is a neurological disorder that exists in sporadic and familial forms and causes the death of dopamine-producing neurons in humans. Rotenone, a pesticide, can be used to induce a model of sporadic ... -
Identification of novel candidate genes involved in resistance against a fungal pathogen in Drosphila melanogaster using the DSPR and QTL analysis
(2015-05)The severity of infection and its effect on organisms differs and has a genetic basis. Though many genes are known to directly play a role in immune pathways, more genes involved in immunity (including those that affect ... -
Immunohistochemical quantification of serotonin and serotonin transporters in the lumbar region of the mouse spinal cord after spinal cord injury
(2013-07-12)Central pattern generators (CPGs) are important neuronal networks that are made up of interneurons that organize rhythmic motor output such as respiration, mastication, and locomotion. Locomotor CPGs are located in the ... -
Kar2 modification as a response to reactive oxygen species generated from protein folding machinery inside the endoplasmic reticulum
(2014-01)Reactive oxygen species are generated as a byproduct of protein folding inside the endoplasmic reticulum. Hydrogen peroxide is a particular form of reactive oxygen that can damage and modify DNA as well as cellular proteins. ... -
Lamiaceae: A source of nootropics with utility in neurodegenerative diseases
(2015-05)Nootropics are ingestible products that are presumed to improve mental functions such as cognition, memory, intelligence, motivation, attention, and concentration; and, are thought to work by altering the availability of ... -
Line tension and bending energy: Understanding the effects on phase separation and the formation of modulated phases
(2015-05)A chemically simple four-component model of animal cell plasma membranes can mimic some important properties of the far more complex biological mixture. In the compositional region of the model mixture where co-existing ... -
Look before you leap: Visual navigation and terrestrial locomotion of the intertidal killifish Fundulus heteroclitus
(2016-05)Mummichogs (Fundulus heteroclitus; Cyprinodontiformes) are intertidal killifish that can breathe air and locomote on land. Our goals were to characterize the terrestrial locomotion of mummichogs and determine their method ... -
Macrophage plasticity and manipulation of macrophage activation pathways by intracellular parasite toxoplasma gondii
(2013-05)See thesis pdf (due to special character formatting) -
Mutagenesis of a conserved cysteine in the Hsp70 molecular chaperone BiP: Impact of amino acid substitution on BiP’s ability to protect cells against endoplasmic reticulumderived oxidative stress
(2015-01)Recently, it has been shown that oxidative protein folding in the endoplasmic reticulum (ER) produces potentially significant amounts of cellular reactive oxygen species (ROS). Although ROS accumulation can cause profound ... -
Neuromodulator and olfaction deficits in an MPTP mouse model of Parkinson's Disease
(2015-01)The aim of this project is to quantify the olfactory dysfunctions associated with Parkinson’s Disease in a mouse 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) model. Parkinson’s Disease, like many neurodegenerative ... -
Novel epoxide-based glutamate agonist class of pesticide: Synthesis, binding mechanism, and potency
(2014-05)Global food production poses one of the greatest challenges for the planet in coming decades, and synthesis of next generation safer pesticides ranks among the important methods in combating this challenge. The vast majority ... -
Optimization of non-viral transfection methods for equine mesenchymal stem cells
(2013-05)Mesenchymal stem cells (MSCs) have exciting medical potential, especially those that are genetically modified. Non-viral methods for genetic modification present several advantages over viral methods, and hence, such methods ... -
Optimization of non-viral transfection methods for equine mesenchymal stem cells
(2013-05)Mesenchymal stem cells (MSCs) have exciting medical potential, especially those that are genetically modified. Non-viral methods for genetic modification present several advantages over viral methods, and hence, such methods ... -
Parsing complex community interactions with regulators and non-governmental organizations in relation to local environmental management at Honeoye Lake, New York
(2019-05)This research sought to understand the complex interactions between governmental and non-governmental organizations engaged in assessing or managing the environmental issue of cyanobacterial blooms (commonly known as harmful ... -
Population Scale Transcriptome Profiling from Mixed Samples using Single-Cell Analysis
(2017-05)One powerfull tool in understanding how genetic variations can lead to changes in gene expression across human population involves measuring mRNA expression levels in large scale, with high-throughput sequencing. Still, ... -
Potential genetic causes for sexual dimorphism in immune response of Drosphila melanogaster in respose to infection with the fungal pathogen Beauberia bassinan
(2015-05)The innate immune response is an organism’s first line of defense against disease, be it bacterial, viral, or fungal infection, and it is an integral part of the evolutionary survival of any species. A well-studied model ... -
Socioeconomic status and the brain: A fuzzy-trace theory approach to address concussion underreporting
(2019-05)A growing body of evidence suggests that concussions in both adolescents and young adults are often overlooked, underreported, and inadequately treated. Failing to report symptoms associated with a concussion frequently ...
