Non-suppurative cerebellitis and cerebellar atrophy due to Neospora caninum infection in a Labrador Retriever mix
An adult female spayed Labrador Retriever mix presented to the Cornell University Hospital for Animals’ Emergency Service for a two-week history of progressive ataxia. Suspecting intervertebral disc disease, the patient had been prescribed prednisone by the referring veterinarian. The patient was adopted from a shelter and had no pertinent medical history. On physical exam, the patient exhibited hypermetria, titubation, and intention tremors. Magnetic Resonance Imaging (MRI) revealed cerebellar atrophy and cerebellitis. Cerebrospinal fluid analysis revealed eosinophilic pleocytosis. Titers for Toxoplasma gondii, Neospora caninum, Rickettsia rickettsii, and Canine Distemper Virus were submitted. A 4DX SNAP was performed for tick-borne diseases. The patient was prescribed doxycycline, trimethoprim sulfamethoxazole, clindamycin, folic acid, and prednisone. Serum titers were positive for Neospora caninum. This case report reviews the differential list and diagnostic plan for adult-onset, progressive cerebellar ataxia and discusses the disease process, treatment, and prognosis for adult dogs affected with neosporosis.
Senior seminar paperSeminar SF610.1 2014
Dogs -- Parasites -- Case studies