Now showing items 1-20 of 37

    • An Alternate Treatment for End Stage Coronary Artery Disease: Transmyocardial Laser Revascularization (TMR) 

      Danny, Catropa; Dines, Megan; Kimmel, Jeremy; Rubin, Juli; Nocerino, Christina (2003-06-17)
      Coronary artery disease involves the buildup of plaque (from cholesterol) on the inside of the arteries, which limits the flow of blood through the vessel. Occlusion of these vessels leads to angina and ultimately to ...
    • Assessing the Effects of Icing the Body for 20 Minutes 

      Chin, Jonathan; Pham, Hubert; Steck, Alaina; Sterman, Sarah; Sun, Mindy (2004-07-13)
      Icing is one of the most inexpensive and convenient treatments available to reduce inflammation in sore and injured muscles. A commonly purported icing regimen follows a ?20 minutes on, 20 minutes off? cycle, so we ...
    • Breaking the Skin Barrier: Modelling Microneedles for Transdermal Insulin Delivery 

      Kang, Jeniffer; Lee, Amy; Lee, Julie; Sadikin, Felicia (2016-05-16)
      Transdermal patches, devices developed to deliver drugs, can be limited in their efficacy because the amount of drug that diffuses through the skin often doesn’t reach sufficient concentrations. This problem is alleviated ...
    • A Computer Model for Evaluating the Efficiency of Cryosurgery for Prostate Cancer 

      Horsfield, Michael; Sarkar, Ritvik; Reffsin, Sam; Seog, Woo Jin (2016-05-16)
      We model the effects of the cryosurgery process for prostate cancer in COMSOL Multiphysics® (ver 5.1) using imaging and manufacturing data to generate 3D realistic geometry for the prostate and cryoprobe. By imposing a ...
    • Cryopreservation of the Kidney: A Feasibility Study Based on Cooling Rates 

      Malvica, Erica; Salter, Ben; Verma, Kush; Watkins, Tara; Shauhgnesy, Michael (2003-07-12)
      This project models the cryopreservation of a kidney submerged in liquid nitrogen. Attempts to cryopreserve whole organs have been unsuccessful in the past due to the formation of ice crystals in the intracellular fluid, ...
    • Cryopreservation of Umbilical Cord Tissue for Stem Cell Harvesting 

      Buchwald, Steven; Chiu, Nicole; Chu, Melvin; Kim, Hesed; Yeang, Calvin (2003-07-12)
      Stem cell transplantation has become an important process used to treat patients with bone marrow diseases. When implanted into patients, stem cells from the umbilical cord have been found to successfully proliferate as ...
    • A Cryosurgical Approach to Lung Cancer 

      Cabrera, Edgar Allen; Mullaney, Kerry; Ramirez, Marina (2004-07-13)
      Lung cancer is the second leading cause of death in the United Statesi, presenting the need for more refined treatment options than traditional invasive surgery and chemo- and radiation therapy. This study investigates the ...
    • Cupric Ion Release from Various IUD Geometries 

      Hernández, Sascha; Riggs, Lauren; Widjaja, Edison (2016-05-16)
      Intrauterine Devices (IUDs) are gaining popularity as a form of long-acting reversible contraceptives (LARC); once inserted, copper IUDs can be effective for up to ten years and require no action from the user. The ...
    • Diffusion and Binding of Radio-Labeled Antibodies in a Tumor 

      Schweitzer, Andrew; Su, Wan-Lin; Benlifer, Adam; Mathrani, Vikram; Aarismaa, Linda (2004-07-13)
      With the decreasing cost of monoclonal antibody production, radioimmunotherapy (RIT) has rapidly emerged as one of the more promising methods of treating cancer cells. RIT makes use of radio-labeled monoclonal antibodies ...
    • Drug Delivery from PLGA-Coated Stents: Optimization of Strut Geometry and Extent of Embedment in the Arterial Wall 

      Ernst, Alexander; Gainey, Shelby; Jusuf, Sebastian; Li, Jingrui (2016-05-16)
      Patients with atherosclerosis experience plaque buildup in the coronary artery, reducing blood flow and increasing the likelihood of a blood clot. Balloon angioplasty and the implantation of a metal stent are physical ...
    • Endovenous Laser Treatment for Occlusion of Varicose Veins 

      Bai, Lillia; Cullopulli, Sherya; Nadeau, Sarah (2016-05-16)
      Endovenous laser treatment (ELT) is a minimally invasive technique that uses laser energy to treat varicose veins. An optical fiber is inserted under the guidance of ultrasound and laser light is shone into the interior ...
    • Finite Element Modeling of Thermal Regulation in Extra Vehicular Activity 

      Biswas, Rohit; France, Emma; Paradkar, Mihir; Woods, Zach (2016-05-16)
      Astronauts perspire heavily during the strenuous exercise of Extravehicular Activity (EVA), and previous literature has expressed concern that this may negatively impact the ability of the LCVG to maintain thermal comfort. ...
    • Frostbyte: Multi-Phase Lower Digital Freezing 

      Cooke, Benjamin; Jaicks, John; Kitzinger, Cameron; Sheppard, TJ (2021-05)
      Though frostbite is an affliction that has been commonly known for hundreds of years, its direct effect and dynamics have rarely been studied. With modern technology and an understanding of the human body, tissue freezing ...
    • Hearts Ablaze: Radio Frequency Ablation as Treatment for Cardiac Arrythmia 

      gillen, kelly; greenberg, jason; pevsner, sam; rounds, becky; schneller, quinn (2003-06-17)
      This project analyzes several of the parameters involved in the use of radiofrequency ablation (RFA) in the treatment of cardiac arrhythmia. Arrhythmia is an irregular beating of the heart that can be caused by improperly ...
    • Heat Transfer in Laser Tumor Excision 

      Chen, Alan; Cheung, Edwin; Lee, Steven; Picuri, John; Shih, Tsung Li (2004-07-13)
      Cancer is an ongoing disease that is present in a majority of the population. Laser surgery provides minimally invasive techniques to excise tumors in humans. This method allows quicker recoveries and fewer complications. ...
    • How Warm is an Igloo? 

      Holihan, Rich; Keeley, Dan; Lee, Daniel; Tu, Powen; Yang, Eric (2003-06-17)
      Homeostasis maintains the human body temperature within a few degrees of 37oC. However, in severe environments, such as a harsh winter blizzard, the body will not be able to maintain a 37oC temperature without the aid ...
    • Hyperthermic Ablation of Hepatic Tumors by Inductive Heating of Ferromagnetic Alloy Implants 

      Androlowicz, Julie; Clark, Iain; Doerr, Georgr; Netravali, Nathan; Wynne, Joseph (2003-06-17)
      This study is an investigation into the ability of ferromagnetic thermal therapy to destroy cancerous hepatic tissue. Ferromagnetic rods are implanted in cancerous tissue and heated by induction. Increased temperatures ...
    • In Vitro Scaffold Construction for a Bio-artificial Liver 

      Webster, Brad; Jong Kim, Tak; Chow, Sharon; Wang, Jeff; Tsai, Chrissy (2004-06-17)
      The main focus of this investigation is to design a scaffold that will accommodate a growing Bio-Artificial Liver (BAL) with oxygen. The two design objectives are to find the maximum length and the distance between the ...
    • An Injectable Oxygen and VEGF Releasing Hydrogel for Cardiac Tissue Regeneration 

      Li, Linda; Lubinus, Ariadna; Murundi, Shamanth; Prakash, Gayatri (2021-05)
      The purpose of this study was to determine the design requirements of an injectable fibrin hydrogel as a viable tool in delivering sufficient oxygen (O2) and vascular endothelial growth factor (VEGF) to hypoxic tissue to ...
    • Lord of the Mood Rings 

      Celia, Chan; Yen, Cu; Jessica, Kadlec; Jennifer, Lee (2003-06-17)
      Our main objective is to study the mechanisms by which heat transfer taking place in the human finger will affect the color change in the mood ring. This project uses GAMBIT and FIDAP to model the heat transfer from the ...