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Browsing Biological and Environmental Engineering by Title
Now showing items 168-187 of 297
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Modeling and Optimization of a Bioartificial Implant to Alleviate Diabetes
Hung, Ben; Fe, Alex; Schmidt, Greg (2008-07-23)Diabetes is a chronic disease that is characterized by a person having too high blood sugar levels due to the deficiency of insulin. If left untreated, there is serious risk for development of cardiovascular diseases, renal ... -
Modeling and Optimizing High Pressure Liquid Chromatography (HPLC) Columns for the Separation of Biopharmaceuticals
Huang, Alex; Huang, Dantong; Yuan, Jie (2013-05-30)One of the most critical steps in the production of pharmaceuticals is the separation of the desired compound from reaction byproducts and environmental contaminants. Among the most sensitive of these methods is High ... -
Modeling Brain Cooling Helmets for Ischemia Patients
Wiechecki, Julie; Ranganath, Neel; McDonough, Brendan; Wind, Jessica (2010-05-21)In this project, we modeled the effectiveness of a cooling cap designed to lower brain temperatures by approximately 3°C in order to cause temporary hypothermia in the brain and thereby prevent further injury caused by ... -
Modeling brain cooling treatment approved for hypoxic-ischemic encephalopathy in infants to treat stroke and cardiac arrest in adult patients
Christiansen, Michael; Rakhilin, Nikolai; Tarakanova, Anna; Wong, Kevin (2012-01-18) -
Modeling Carmustine Diffusion from Gliadel® Wafers in the Brain to Optimize Cancer Treatment and Minimize Damage to Healthy Tissue
Azar, Julian; Elacqua, Joshua; Peñaranda, David; Stone, Alexander (2016-05-16)Gliadel® wafers have been developed to circumvent traditional obstacles in brain cancer treatment. Chemotherapeutic drugs administered intravenously are rendered largely ineffective by the blood-brain barrier. Gliadel ... -
Modeling Concentration Profiles of Infliximab in Colon Wall to Ensure Efficacy of Drug-Eluting Biodegradable Stent in the Management of Crohn's Disease
Dennin, Sean; Li, Xing; Yang, Danrui (2013-05-30)Crohn’s disease (CD) is a chronic inflammatory disorder of the bowel affecting more than 500,000 people in the US. Current delivery mechanisms for CD medications lack site and time specificity. Advances in biomaterials ... -
Modeling Countercurrent Arteriovenous Heat Exchange and Blood Flow in a Finger Exposed to Cold
Albano, Greg; Slowskei, Lauren; Puckett, Lee; Reynolds, Aaron (2018-05-09)It is widely accepted among the scientific community that countercurrent heat exchange between blood vessels developed as an advantageous evolutionary trait for preserving body heat in humans and other animals; however, ... -
Modeling Dye Assisted Photocoagulation of Age-Related Macular Degeneration
Cadesky, Lee; Suh, Jun Hyuk; Tian, Hongyi (2014-05-28)Age-related macular degeneration (AMD) is major cause of blindness in Americans aged 50 years and up. In 2010, there were more than 2 million cases of AMD in the United States and the National Eye Institute projects that ... -
Modeling Flow Characteristics in Carotid Artery Bifurcation Afflicted with Atherosclerotic Plaques
Braun, Alexandra; Ford, Stellie Justin; Shumakovich, Marina; Sonnenfeldt, Alden (2013-05-30)Atherosclerosis is a condition characterized by the hardening of arteries due to the buildup of fatty substances, dead monocytes, and oxidized LDL particles. In advanced cases, atherosclerotic plaques form within artery ... -
Modeling Heat Exchange in Spatial Steering of Deep Brain Stimulation
Mitchell, Matthew; Barghouthi, Khalid; Rebec, Mihailo (2014-05-28)Deep brain stimulation (DBS) is a treatment that involves insertion of a probe and stimulation of brain tissue with an electric potential (or injection of current). Electrical stimulation has been demonstrated to be an ... -
Modeling Heat Flows in a Hibernating Black Bear
Cottrell, Jocelyn; Hogan, Chris; Jain, Nieraj; Nogal, Bartosz; McWay, Michael (2003-07-12)The American Black Bear (Ursus americanus) has the ability to sustain a high core temperature throughout the duration of its hibernation cycle, even as outside temperatures fall to -20?C. This ability is largely due the ... -
Modeling Heat Transfer in the Eye during Cataract Surgery
Akkar, Sona; Bharadwaj, Koonal; Paya, Naweed; Shai, Adam (2009-05-08)Cataract surgery is one of the most commonly performed surgical procedures in the world, and it involves using a technique called phacoemulsification. With this technique, the cloudy, crystalline lens in the eye is ... -
Modeling Heat Transfer of Intradiscal Electrothermal Catheter Therapy for Low Back Pain
Waldron, Caitlin; Walden, Lauren; Yoo, Michael; Chae, Sun (2012-08-29) -
Modeling Heat-Transfer of the Olympic Cool-Cap System(R)
Pathak, Kalpana; Yu, Nansen; Shoffstall, Andrew; Zheng, Laura (2008-07-23)Hypoxic-ischemic encephalopathy (HIE), or brain damage due to low blood flow and oxygen deprivation, causes 6 deaths per 1,000 births (Long and Brandon 293). HIE can be caused by cord prolapse, abruptio placentae, maternal ... -
Modeling Hot Air Flow in the Trachea to Minimize Burn Damage
Browning, Katharine; Chiang, James; Datta, Ankurita; Modi, Sarah (2012-05-03) -
Modeling NK Cell Toxin Diffusion
Bryan, Michaela; McLane, Liam; Park, Andy; Tjokorda, Indira (2022-05-27)Natural killer (NK) cells are a key part of the body’s innate immune system, killing cells that have been damaged or stressed by infection and controlling the spread of disease while a slower, more powerful adaptive immune ... -
Modeling of Antibiotic Diffusion from Implanted Absorbable Beads in Localized Injured Tissue
Grant, Kara; Lawson, Olivia; Polins, Ben; Suen, Leslie (2010-05-21)Prevention of infection during the healing process in tissue is a major concern and is especially crucial for the health of the patient. In order to combat infection due to bacteria, antibiotics must be deployed in the ... -
Modeling of Primary Freeze Drying Phase of Lyophilization of Ebola Virus Disease Vaccine
Adams, Abby; Flood, Donovan; Ganesan, Sandhya; Koga, Maho (2020-05)Lyophilization, or freeze-drying, is a commonly used technique to extend the shelf life and increase the stability of various pharmaceuticals by removing excess water from the product. The process can be energy and ... -
Modeling Oxygen Flow through Continuous Wear Contact Lens-Cornea System with Increasing Protein Layer Build-up
Lee, Nancy; Day, David; Choi, Semyung; Lim, Nansae; Kuo, Johnathan (2006-01-16) -
Modeling Particulate Wash-Off on Rough, Impervious Surface: Field Environments
Lebowitz, Molly (Internet-First University Press, 2005-08-03)This is a poster presentation exploring the research in pariculate wash-off of impervious surfaces.