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Browsing Biological and Environmental Engineering by Title
Now showing items 204-223 of 297
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Optimization of Chemotherapy for Lung Cancer
Beelitz, Carolyn; Bui, Jojo; Connelly, John; Mukherjee, Rani; Pan, Katy (2001-01-07)Chemotherapy is a common treatment method for lung cancer. Using FIDAP, this study simulated the diffusion of the drug, Cisplatin, from the blood stream throughout a lung tumor that partially blocked an airway. Two ... -
Optimization of Combined Radiation and Gold Nanoparticle Hyperthermia Therapy for Treating Cutaneous Squamous Carcinoma
Sankar, Sitara; Zhang, Michelle (2015-05-19)Radiation therapy offers the ability to kill and shrink tumors non-invasively and serves as adjuvant therapy post-surgery and as primary therapy for patients unable to undergo surgery. But the process is nonspecific and ... -
Optimization of Contact Lens Drug Delivery to Ocular Tissue
Barsoum, Kyrollos; Kureshi, Rakeeb; Lee, Carina; Pacifici, Noah (2016-05-16)Intraocular pressure is a risk factor for developing glaucoma, a disease that damages the optic nerve and can result in vision impairment. Timolol is a beta-adrenergic antagonist that decreases intraocular pressure (IOP) ... -
Optimization of Coventional pMDIs for a Better Salutamol Delivery System
Luu, Ha (Natalie); Lin, Kimberly; Contreras, Danya; Curley, Stephanie (2013-05-30)The most commonly prescribed method of treatment for asthma today is the pressurized metered dose inhaler (pMDI). However, many patients fail to use it correctly, resulting in the inefficient administration of the drug. ... -
The Optimization of Gentamicin Concentration in Diffusion Analysis for Bone Cement of Total Hip Arthroplasty
Singh, Chris; Park, Sunjoo; Bendit, Henry; Allen, Melissa (2012-01-18) -
Optimization of Hydrogel-based Cellular Encapsulation for Diabetes Treatment
Bao, Ed; Shariati, Kaavian; Alimena, Nicole; Mehrabyan, Tigran (2018-05-10)Cell encapsulation is an efficient and cost-effective treatment for a variety of endocrine and hormonal disorders. The use of cells to deliver therapeutics is an especially desirable means drug delivery may be achieved, ... -
Optimization of Laser Ablation Parameters for Lumbar Discectomy
Ashraf, Shaumik; Chan, William; Delgado, Robert; Hassan, Mohamed (2019-05)Lower back pain, or lumbar pain, is a potentially debilitating chronic condition that will affect an estimated 80% of individuals in their lifetime. Lumbar pain can be caused by herniated lumbar discs, which is ... -
Optimization of Nicotine Patch Placement
Barten, Garrett; Buhmann, Brendan; Gordon-Messer, Susannah; Kaufman, Aaron; Ward, Briana (2004-11-12)Nicotine patches are currently used as a transdermal drug delivery method help to people trying to quit smoking. Currently, those trying to quit smoking are encouraged to place the nicotine patch on the outside of the upper ... -
Optimization of Oral Insulin Drug Delivery via Inhalation
Chin, Karen; Mulchan, Nicholas; Hong, Stephen; Yoon, Stephen (2013-05-30)Drug inhalation is quickly emerging in the field of drug delivery techniques, providing localized treatment for various types of lung disorders. To expand oral drug delivery, this project will focus on inhaled insulin ... -
Optimization of reversible electroporation for the destruction of an irregular brain tumor
Ahmad, Taha; Putrevu, Karann; Walk, Remy; Zhang, Xuexiang (2015-05-19)The ability to localize treatments is of great relevance to many diseases, from cancer to blood clots. The drugs used for treatment are often cytotoxic or otherwise deleterious to healthy as well as diseased tissue, and ... -
Optimization of Transdermal Drug Delivery by Hydrogel-Enhanced Sonophoresis
Chapin, Nate; Hung, Michelle; Larsen, Wesley; Pramil, Varsha (2015-05-19)External-field mediated transdermal drug delivery is a new alternative to oral delivery and hypodermic injections. This method allows patients to receive treatments via a drug-infused patch applied to the skin and offers ... -
Optimization of Transdermal Drug Delivery with Microcapsules
Jackman, Monica; Kim, Nala; Kim, Sung Min; Wong, Bethany (2010-05-21)Research in transdermal drug delivery systems has gained much attention in the past thirty years. One of the biggest challenges in developing an effective system however, is getting past the tightly-structured outermost ... -
Optimized Injection Site Location for Magnetic Nanoparticle Induced Hyperthermia Cancer Treatment
Hall, Matthew; Yanga, Dennis; Yi, Kevin; Zhou, Jiachi (2012-05-03) -
Optimizing Combined Laser Treatment for the Removal of Port Wine Stains and Cryogen Spray Cooling to Reduce Thermal Heating at the Skin Surface
Agustin, Marissa; Jimenez, Rod Brian; Berglund, Caroline; Mookerjee, Adaleena (2010-05-21)Port wine stains (PWS) are birthmarks caused by the presence of dilated blood vessels, typically 15-55μm in diameter, located in the upper dermis of the skin. Currently, lasers in conjunction with cryogen cooling are the ... -
Optimizing diffusion time prior to probe-mediated microwave heating of injected nanoparticles for hyperthermia treatment of tumors
Enderlein, Colin; Guarecuco, Rohiverth; Lizarralde, Rafael; Rasmussen, Erik (2013-05-30)Localized tumor hyperthermia therapy is a treatment that involves heating cancerous tissue to temperatures that result in tumor cell necrosis, while preventing damage to surrounding healthy tissue. Hyperthermia therapy ... -
Optimizing Nitrogen Fertilizer Quantities in Cereal Crop Root Systems to Minimize Leaching
Kuelbs, Chloe; Liu, Jiren; Sadoff, Hunter; Shen, Jeffrey (2022-05-27)Loss of nitrogen due to leaching is one of the most pressing issues in agriculture as it leads to excessive crop production costs and pollution. N leaching contributes to atmospheric and aquatic pollution [1]. The production ... -
Optimizing Release from Reservoir Microcapsules
Hoang, David; Liu, David; Chen, Jennifer; Siu, Vince (2007-07-10)Cytomegalovrius (CMV) retinitis is a common symptom of vision loss found in 20-30% of all acquired immunodeficiency syndrome (AIDS) sufferers. While there are no drugs that can cure permanent retinal damage by CMV, the ... -
Optimizing Shear for Neural Stem Cell Differentiation
Steinhagen, Dustin; Ravelo, Gabrielle; He, Sophia (2017-05-19)Neural stem cells (NSC) have great potential for use in treatments for neurological disease by replacing damaged brain tissue via transplantation therapies. Growing NSC can be challenging, since the environment that the ... -
Optimizing Throughput in a Fetal Cell Magnetophoretic Separator
Flood, Zachary; Jasty, Naveen; Jiang, Chiyu; Park, Jino (2015-05-19)Magnetophoretic separation is a non-invasive method under development for the sampling of nucleated fetal red blood cells (NRBCs). By inducing a magnetic field gradient symmetrically about a microfluidic separatory ... -
Optimizing Ultrasonic Intensity for High Intensity Focused Ultrasound Therapy
Carter, Matt; Sullivan, Art; Byers, Kenny; Jessel, Michael (2014-05-28)Every year as many as one million individuals worldwide are diagnosed with hepatocellular carcinoma (HCC), the most common form of liver cancer. Caused by cirrhosis, HCC is typically treated with surgery or chemotherapy. ...