Foote, Stacey; Gaines, Carmen; Levine, Jacob; Pecak, Garry; Saikkonen, Kelly
Heart disease affects many people and heart transplants are becoming more common. Limited shelf life is a major hindrance to the success of heart transplants. Cryopreservation opens an avenue for increasing shelf life. Our goal in this study was to model the preservation of a heart using finite element software to determine the time needed to sufficiently cool the heart and to compare the average temperature to the maximum temperature of the heart. We found a range of minimum times varying with material properties of the heart. We concluded that computer simulation can be used to approximate the minimum time needed to reach a desired maximum temperature. We also found that average temperature of the heart during cooling was not an accurate approximation of the maximum temperature.
No access to the full paper due to lack of a FERPA release.