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dc.contributor.authorBazzle, Lisa
dc.description.abstractMegaesophagus is a diffuse or focal esophageal hypomotility disorder attributed to either a myopathy, neuropathy, or junctionopathy with a broad range of potential etiologies. The differential diagnoses are discussed as it relates to a case of a 5 year old, mixed-breed dog with megaesophagus, cranial neuropathy, and progressive myopathy. A presumptive diagnosis of Neosporosis was made, and despite treatment, the patient later developed generalized muscle atrophy. Biopsies of the affected muscles were taken revealing an immune-mediated polymyositis, a sequela attributed to previous infection with Neospora caninum. The pathogenesis of Neosporosis as it contributes to the patient’s clinical presentation, its role in the development of immune-mediated polymyositis, as well as the management of chronic megaesophagus and polymyositis is discussed.en_US
dc.relation.ispartofseriesSenior seminar paper
dc.relation.ispartofseriesSeminar SF610.1 2010
dc.subjectDogs -- Diseases -- Case studiesen_US
dc.titleMegaesophagus and progressive myopathy in a 5 year old dogen_US
dc.typeterm paperen_US

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