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dc.contributor.authorMcGlashan, Stacy
dc.date.accessioned2008-09-07T22:08:33Z
dc.date.available2008-09-07T22:08:33Z
dc.date.issued2004-09-15
dc.identifier.urihttps://hdl.handle.net/1813/11347
dc.description.abstractA 3 month old 120 kg thoroughbred colt presented with a chief complaint of diarrhea, depression, fever, and inappetence with no history of respiratory illness. He was treated but his signs did not resolve and he succumbed to his disease. Postmortem findings included severe, diffuse chronic pyogranulomatous abdominal lymphadenitis, lymphangitis, and lymphangiectasia with severe, diffuse chronic neocroulcerative pyogranulomatous enterocolitis and typhlitis, and severe, chronic multifocal pyogranulomatous bronchopneumonia. The presumptive diagnosis was Rhodococcus equi, which was confirmed with bacteriology and histology. Rhodococcus equi (R. equi) is a gram-positive facultative anaerobic bacterium, characterized as an opportunistic pathogen that lives and replicates within host macrophages. This bacteria?s ability to retain viability within macrophages may be due to a delay in maturation of phagosomes to phagolysosomes. Although most horse farms contain R. equi in the enivronment, several factors contribute to the role of this bacterium as a pathogen. Since complete prevention is not possible, early detection and treatment is critical. The treatment of choice is a combination of a macrolide (erythromycin, clarithromycin or azithromycin) with rifampin.en_US
dc.language.isoen_USen_US
dc.relation.ispartofseriesSenior seminar paperen_US
dc.relation.ispartofseriesSeminar SF610.1 2005 M44
dc.subjectHorses -- Diseases -- Case studies
dc.subjectHorses -- Infections -- Case studies
dc.titleSevere intestinal rhodococcus infection in a Thoroughbred colten_US
dc.typeterm paperen_US


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