Now showing items 1-20 of 212

    • 3D modeling of aflibercept transport in the vitreous humor 

      Li, Kevin; Limjoco, Matthew; Zarate, Jason (2017-05-11)
      Aflibercept is an anti-vascular endothelial growth factor (anti-VEGF) drug used to treat several retinal diseases such as macular degeneration. It accomplishes this by binding and inhibiting VEGF, which is the growth factor ...
    • The ABC's: Atherosclerosis, Blood Flow, and the Carotid Artery 

      Beers, Craig; Jennifer, Burlingame; Johnson, Leigh Ann; Stepp, Eliza (1999-01-10)
      The effects of blood flow were analyzed in the carotid artery, using computer aided engineering software (FIDAP and GAMBIT). The study was conducted because patients that have atherosclerosis often have plaque build up ...
    • Accidental Freezing of the Tongue to Metal Poles 

      Gurzo, Mike; Ho, Jeremy; Lally, Sean; Selig, Mike (2000-01-10)
      In an attempt to verify the age-old claim that your tongue will freeze to a metal pole and become stuck if you decide to lick it in the midst of winter, we have modeled tongue contact with a cold metal surface using ...
    • The Advantage of Under Armour for Winter Sports Performance 

      Allen, Lisa; Chen, Brenda; Pokwal, Sonam; Graunke, Steve (2006-05-24)
      Under Armour produces apparel designed for winter sports athletes. This apparel aims to keep athletes comfortable by retaining body heat and removing moisture due to perspiration. Special wicking properties are claimed to ...
    • Albuterol Uptake in Bronchioles 

      Ho, Jeff; Putnam, Lauren; Savath, Vince; Scott, Bill (2004-11-12)
      Millions of people around the world suffer from asthma, which is characterized by breathing problems due to constricting bronchioles. While current remedies involve an effective inhaler drug, such as Albuterol, that relieves ...
    • An Alternate Treatment for End Stage Coronary Artery Disease: Transmyocardial Laser Revascularization (TMR) 

      Danny, Catropa; Dines, Megan; Kimmel, Jeremy; Rubin, Juli; Nocerino, Christina (2003-06-17)
      Coronary artery disease involves the buildup of plaque (from cholesterol) on the inside of the arteries, which limits the flow of blood through the vessel. Occlusion of these vessels leads to angina and ultimately to ...
    • An Analysis of the Ortho Evra Birth Control Patch 

      Fields, Rachel; Fisher, Elana; Kramer, Scott; Kwan, Elaine; Wong, Angela (2006-05-24)
      The Ortho Evra Birth Control Patch is an effective alternative method of birth control. It releases two drugs, norelgestromin and ethinyl estradiol, and these two drugs diffuse through a person?s skin and into their ...
    • Angina Patch: Drug Delivery for Chest Pain 

      Lee, Jessica; Morgan, Lee; Yee, Jackie (2006-05-24)
      Angina pectoris is defined as chest pain due to lack of blood and oxygen to the heart. Nitroglycerin is an organic nitrate which treats angina by vasodilating both arteries and veins to increase blood flow to the heart. ...
    • Angiography 

      Fryman, Rodney Sean; Jarrad, Daniela Elizabeth; Lau, Christina Mei Lan; Raile, Benjamin William (1999-01-10)
      This paper explores the use of Computer Aided Engineering (CAE) to model angiography dye flow in the detection of cerebral aneurysms. To obtain a discernable image, the concentration of the dye, Conray-60 ? , needed to be ...
    • Antibiotic Releasing Biodegradable Sutures for the Prevention of Surgical Site Infections 

      Bowen, Caitlin; Kersbergen, Calvin; Rappazzo, C. Garrett; Weed, Beth (2014-05-28)
      Although a necessary component of surgery, sutures have been shown to exhibit an affinity for microbial adherence and colonization. The sutures offer a conduit for bacteria directly into the wound and infection can be ...
    • Application of Computational Tear Flow Models to Smart Contact Lens Design 

      Ashley, Ryan; Fida, Marsela; Li, Jeffrey; Ly, Jeffrey (2014-05-28)
      Millions of diabetics could benefit from a noninvasive and cheaper method for monitoring their blood glucose. A solution recently popularized by Google makes use of smart contact lenses featuring embedded glucose sensors ...
    • Assessing the Effects of Icing the Body for 20 Minutes 

      Chin, Jonathan; Pham, Hubert; Steck, Alaina; Sterman, Sarah; Sun, Mindy (2004-07-13)
      Icing is one of the most inexpensive and convenient treatments available to reduce inflammation in sore and injured muscles. A commonly purported icing regimen follows a ?20 minutes on, 20 minutes off? cycle, so we ...
    • AutoSyringe Injection: Mass transfer driven by plunger to force medication through a needle 

      Billington, Alicia; Deyle, Alex; Ippolito, Andrea; Kim, Jennifer; Weaver, Matt; Weitsman, Andrew (2006-05-24)
      The AutoSyringe is an automatic device that allows patients with limited dexterity to administer medication to themselves as painlessly as possible. The device allows patients to inject themselves subcutaneously, where ...
    • Bald is Beautiful, but is it Warm? 

      Dy, Eric; Ross, Rachel; Tataria, Jigar; Lundeen, Anna (2004-11-12)
      The head is a major source of heat loss (60-80%), and therefore, if conditions are cold enough, not keeping the head properly insulated could lead to hypothermia. Because of this, we were interested in determining to what ...
    • Betamethasone Phosphate Drug Delivery by Biodegradable Ocular Implant 

      Chari, Tara; Li, Catherine; Varghese, Rebecca; Yang, Qiuwei (2017-05-17)
      Biodegradable implants have been steadily gaining popularity, offering safer, more efficient alternatives to common therapeutics. Currently, most ocular implants that are used for sustainable drug delivery are non-biodegradable. ...
    • Biodegradable Implant with TGF-beta Delivery for Enhanced Healing of Bone Tissue: A Computational Model 

      Eckes, Kevin; Post, David; Sutermaster, Bryan; Villarreal, Sarah (2009-05-08)
      In most common fractures, bone is able to heal itself over a six week time period. Catastrophic fractures, however, may require that shards of bone be removed surgically, leaving critical size defects in fracture areas ...
    • Breaking the Skin Barrier: Modelling Microneedles for Transdermal Insulin Delivery 

      Kang, Jeniffer; Lee, Amy; Lee, Julie; Sadikin, Felicia (2016-05-16)
      Transdermal patches, devices developed to deliver drugs, can be limited in their efficacy because the amount of drug that diffuses through the skin often doesn’t reach sufficient concentrations. This problem is alleviated ...
    • Chemotherapuetic Treatment Using Controlled Drug Delivery of BCNU via Nanoparticles 

      Brendel, Matt; Casey, Molly; Gilbert, Rachel; Spinella, Mel (2013-05-30)
      The most common type of brain tumor is the glioma and despite advances in diagnostic imaging and drug delivery, there are no effective cures. This is due to the malignant glioma’s tendency to recur after treatment, with ...
    • Chemotherapy: Drug Diffusion through Solid Tumor 

      Saifi, Comron; Fallick, Jesse; Chen, William; Hsu, Jennifer; Perlmutter, Jason (2006-01-16)