This is a repository of student class project reports for Professor Ashim Datta's BEE 4530/Computer-aided Engineering course. For more details on the course, see http://4530.bee.cornell.edu/.


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  • Modeling NK Cell Toxin Diffusion 

    Bryan, Michaela; McLane, Liam; Park, Andy; Tjokorda, Indira (2022-05-27)
    Natural killer (NK) cells are a key part of the body’s innate immune system, killing cells that have been damaged or stressed by infection and controlling the spread of disease while a slower, more powerful adaptive immune ...
  • How do Laser Pointers Damage your Retina? 

    Lee, Joseph; Kuhikar, Sneha; van der Vliet, Riemer (2022-05-27)
    Lasers are devices used for many applications, for instance, in CD burning and reading, to baffle an audience in a light show or to point out details on a projector. The handheld laser or laser pointer is not given much ...
  • Optimizing Nitrogen Fertilizer Quantities in Cereal Crop Root Systems to Minimize Leaching 

    Kuelbs, Chloe; Liu, Jiren; Sadoff, Hunter; Shen, Jeffrey (2022-05-27)
    Loss of nitrogen due to leaching is one of the most pressing issues in agriculture as it leads to excessive crop production costs and pollution. N leaching contributes to atmospheric and aquatic pollution [1]. The production ...
  • Hydrogel Smart Bandage as a Diagnostic Tool for Infection in Burn Wounds 

    Kelly, Abby; Zhai, Mattieu; Li, Alan; Zhu, Jiaming (2022-05-27)
    Every year, almost half a million people are admitted to the emergency room because of burn wounds. Of the thousands of deaths that result from these wounds, more than half are due to complications from infection. An easy ...
  • Victoria’s Secret Problem: Heat Loss in Mastectomy Patients 

    Chen, Hsin Huei; Irons, Kelly; Lee, Taehee; Mathur, Shubham (2022-05-27)
    Mastectomies are performed to treat or prevent the risk of breast cancer. Annually, over 100,000 women in the US undergo some form of mastectomy [1]. Approximately 40% of women who undergo mastectomies elect to undergo ...
  • Still a Threat: Polychlorinated Biphenyl (PCB) Metabolism in Cells & Formation of Cancer-Causing DNA Adducts 

    Chang, Wei-Ann; Taveras, Alwany Angeles; Saadatmand, Bahareh; Gaul, Larissa (2021-05)
    Despite PCBs having been banned from manufacturing processes for decades, polychlorinated biphenyls or PCBs can still enter the environment through various means, such as improper waste disposal methods, and wreak havoc. ...
  • Frostbyte: Multi-Phase Lower Digital Freezing 

    Cooke, Benjamin; Jaicks, John; Kitzinger, Cameron; Sheppard, TJ (2021-05)
    Though frostbite is an affliction that has been commonly known for hundreds of years, its direct effect and dynamics have rarely been studied. With modern technology and an understanding of the human body, tissue freezing ...
  • An Injectable Oxygen and VEGF Releasing Hydrogel for Cardiac Tissue Regeneration 

    Li, Linda; Lubinus, Ariadna; Murundi, Shamanth; Prakash, Gayatri (2021-05)
    The purpose of this study was to determine the design requirements of an injectable fibrin hydrogel as a viable tool in delivering sufficient oxygen (O2) and vascular endothelial growth factor (VEGF) to hypoxic tissue to ...
  • Murdering the Murder Hornet: Heat and CO2 Exchange in a Bee-ball 

    Shack, Jasmine; Yu, Evelyn (Zichen); Yu, Ruoqian Lin; Fang, Ye (2021-05)
    Bee-balling is a defensive technique employed by Japanese honeybees, Apis cerana japonica, against the predatory Asian giant hornet, Vespa mandarinia. Upon recognition of the hornet intruder within the hive, hundreds of ...
  • A Model of Transdermal Drug Delivery through Electroporation 

    Adair, James; Chou, Emily; Metzloff, Matt; Tse, Truman (2021-05)
    Electroporation is a technique that applies high voltage pulses over short time periods, resulting in strong electric fields, to create micropores in cell membranes. When applied to the skin, electroporation causes Joule ...

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