Over the past 4 months, a pasture-based swine facility has lost about 75 pigs. The facility purchases random source pigs from various suppliers and there are multiple breeds of pigs on the farm. Affected pigs show a variety of signs including: diarrhea, lameness, neurologic issues, weight loss, skin lesions and death. Deceased pigs have shown some or all of these signs. The management practices were observed, reviewed and discussed with the client. A field necropsy was performed on a dead pig and two pigs were brought to the diagnostic lab for necropsy. Differentials include nutritional deficiencies, parasites, and infectious diseases. Plans for future diagnostics and management changes will be discussed.