This dissertation examines and argues the importance of climate in the daily lives of people–individuals and groups alike–in late antiquity. Central to the project is a reformulation of what climate is and how it is active as an historical force. Much of the existing scholarship posits an agonistic, or at least dualistic, separation between people and climate, where the former is best known through textual and material evidence and the latter via scientific proxies. Contrarily, this work argues that, far from being an external force capable of acting on yet existing outside of human society, climate is something that humans make use of, they create with it and create it. Four topics of significance methodological importance to the field of late antique climate history are addressed in four case studies that are anchored in time and place. Each is investigated with full use of relevant textual, material, and paleoscientific evidence. At the same time, each chapter contains an independently significant historical argument regarding a question currently active in the larger discourse of late antique historiography. This demonstrates how climate and perceptions of climate penetrated into every aspect of daily life, that it cannot be considered outside of the other relational discourses within which it was embedded.