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  4. Estimating Equation Methods For Longitudinal And Survival Data

Estimating Equation Methods For Longitudinal And Survival Data

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dyc24.pdf (831.83 KB)
Permanent Link(s)
https://hdl.handle.net/1813/33515
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Cornell Theses and Dissertations
Author
Clement, David
Abstract

This thesis analyzes censored data in recurrent event, longitudinal, and survival settings. In Chapter 2, a straightforward, flexible methodology is proposed to estimate parameters indexing the conditional means and variances of the interevent times in a recurrent event process. In Chapter 3, we analyze discretely and informatively observed multivariate continuous longitudinal data; missingness and terminal events are introduced in Chapter 4. In Chapters 3 and 4, the inter-event times are considered a nuisance and the goal is to estimate parameters driving the longitudinal process. To do this, we propose an innovative conditional estimating equation that can model individual trajectories. Finally, Chapter 5 uses these subject-specific trajectories to estimate parameters indexing the terminal event process and predict future survival for arbitrary subjects.

Date Issued
2011-01-31
Committee Chair
Strawderman, Robert Lee
Committee Member
Hooker, Giles J.
Wells, Martin Timothy
Degree Discipline
Statistics
Degree Name
Ph. D., Statistics
Degree Level
Doctor of Philosophy
Type
dissertation or thesis

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