The marketing of GE crops in commodity agriculture worldwide faces serious challenges The USDA plays a key regulatory role in developing and marketing by ensuring the safe and appropriate use of genetic engineering in the US and bringing the products derived from GE plants to the worldwide marketplace. While the US leads in the development and production of plant biotechnology products, other countries, notably Brazil, are producing and developing domestic GE products. Furthermore, GE crop varieties are being adopted in both Asia and Africa, with large research and development investment taking hampered by the narrow range of useful insecticidal proteins. Major companies within the industry are clearly committed to the deployment of durable GE crop technologies that can be reasonably integrated into a farmer’s resistance management program as the basis for stewardship of the technology.