A 13-year-old male castrated domestic shorthair presented as an emergency appointment to the ophthalmology department at Cornell University Hospital for Animals for evaluation of an anterior lens luxation (ALL) in his right eye (OD). On presentation, general physical examination was unremarkable but ophthalmic examination revealed the following abnormalities: there was a mature cataract OD and a complete lens luxation into the anterior chamber OD; the pupillary light reflex (PLR) was obscured by the luxated lens OD; the menace response was negative OD; there was a corneal sequestrum OS located paraxially with neovascularization superior to the sequestrurn; chronic keratitis characterized by abnormal blood vessel growth into the cornea was noted in both eyes (OU); chronic uveitis was evidenced by rubeosis iridis OU and sphincter iris atrophy was present OU. The patient was admitted into the hospital and an intracapsular lens extraction (ICLE) surgery was performed OD. At the two-week post-operative recheck, a geographic axial retinal scar around the optic nerve head was visualized OD. At the eight-week post-operative recheck diffuse retinal degeneration was observed OD. Ten months later, the patient presented to his primary care veterinarian's office with an IOP of 60mmHg and apparently blind OD. This case report will discuss the etiology, clinical signs, diagnostics, treatment options and prognosis for lens luxation in a cat.