A case report is presented describing the clinical presentation of a five year old, castrated male, German Shepherd dog, who presented to the Cornell University Hospital for Animals Emergency Service on 7/2/03 with chief complaints of anorexia, lethargy, and regurgitation secondary to a previously diagnosed megaesophagus. Diagnostic investigation included a thyroid panel, ANA titer, Acetylcholine receptor antibody titer, ACTH stimulation test, and blood lead measurement, the results of which were all within normal limits, suggestive of idiopathic disease. Subsequent discussion includes review of pathophysiologic mechanisms, differential diagnoses, and management strategies to be employed by the general practitioner in the approach to esophageal disease in the canine patient.