A 10-year-old female spayed Golden Retriever was transferred to Cornell University Hospital for Animal’s Soft Tissue Surgery service for removal of a large abdominal mass. She originally presented to her referring veterinarian for persistent constipation and ribbon-like feces, and radiographs showed a large abdominal mass. At intake, an occluding mass was identified on rectal palpation. Ultrasound and computed tomography exams revealed a proliferative bone lesion originating from the left ilium. A hemipelvectomy and limb amputation were performed to remove the mass. During the surgery, a loosened anal purse-string suture resulted in surgical site contamination. The area was lavaged profusely and closed in a normal fashion. Histopathology identified the mass as a Grade I multilobular osteochondrosarcoma, a rare neoplasia of the flat bones that is most often found on the skull. The patient presented four days later for surgical site dehiscence, and a wound revision surgery was performed to culture and debride the necrotic tissue. Culture revealed multi-drug resistant Enterococcus faecium infection. The patient was switched to oral chloramphenicol and was discharged after four days in the intensive care unit. On recheck 12 days later the patient was ambulating well, and the incision margins were healthy and healing.