A 1-year-old female spayed Standard Poodle was presented after being hit by a car. Immediately after the accident, the patient had 1 or 2 seizures. The initial assessment of the patient was consistent with traumatic brain injury (TBI); she was stuporous and laterally recumbent, with miotic pupils, no menace response, a decreased gag reflex, and absent proprioception. Deep pain and spinal reflexes were present. Besides an open fracture, the rest of her examination was unremarkable. The patient was stabilized with mannitol, head elevation, intravenous (IV) fluid therapy, and analgesia. She was hospitalized with anti-epileptic medications, broad spectrum antibiotics, anti-emetics, IV fluids, analgesia, continuous electrocardiogram and blood pressure monitoring, and supportive care. Over the next 8 days, the patient’s neurologic status improved steadily. On the 9th day, the patient’s right radius-ulna fracture was repaired. The patient was discharged two days later when she was fully bright and ambulatory.