Topics include: [Director's Statement] A Special Place in Veterinary Medicine (Douglas F. Antczak); James A. Baker Institute for Animal Health 1950-2000: Our Vision, Our Mission, Our Goal; Celebrating 50 Years of Research and Discovery; Alumni of the Baker Institute; Institute Research Today: Canine Genetic Mapping Linkage Studies (Gregory M. Acland), Canine Genetics / Genomics Ophthalmic Genetics (Gustavo Aguirre); Equine Immunology Genetics and Reproduction (Douglas F. Antczak); Mucosal Immunity Host-parasite Interactions (Judith A. Appleton); Intestinal and Systemic Anti-nematode Immunity (Robin G. Bell); Cartilage Biochemistry and Osteoarthritis (Nancy Burton-Wurster); Hip Hysplasia osteoarthritis articular cartilage physiology (George Lust); Cartilage Osteoarthritis anemia (James N. MacLeod); Canine Developmental Genetics and Reproduction (Vicki N. Meyers-Wallen); Canine Virology and Infectious Diseases (Colin Parris); Mucopolysaccharidosis oculo-skeletal dysplasia bleeding disorders (Jharna Ray); Looking Ahead to New Discoveries; Building for the Future; Realizing the Vision; Advisory Council.