Herbert Tobias
Research Associate
2007
HENutrSciWeb Bio Page
Current Activities
Current Research Activities
Development of biochemical isotopic standards for techniques applied to the detection of the use of exogenous anabolic steroids in sport doping. Development of comprehensive two-dimensional gas chromatography separation techniques for the measurement of the stable isotopic composition of individual components in complex samples involving isotope ratio mass spectrometry.
Biography
Biographical Statement
As an experimental analytical chemist, Dr. Tobias' research experience includes the development and application of analytical techniques to such areas as the characterization and study of atmospheric and biological aerosols and biomedical analysis.
Before his position at Cornell University, Dr. Tobias was part of a dynamic group at Lawrence Livermore National Laboratory that developed Bioaerosol Mass Spectrometry for the detection of single airborne microorganisms and environmental airborne particulates. An R&D 100 award in for this work in 2005. As a postdoctoral researcher at University of California at Riverside, Dr. Tobias helped develop and apply thermal desorption particle beam mass spectrometry to the study of the chemical formation of organic aerosols that contribute to air pollution (known as smog) and the characterization of diesel exhaust particulates.
Currently, Dr. Tobias is helping to develop standards and novel techiques for the detection of synthetic anabolic steroids used in sport doping by athletes to enhance performance.
Education
08/94-03/97 Cornell University, NY, Ph.D. (Analytical Chemistry)
07/92-07/94 Cornell University, NY, M.S. (Analytical Chemistry)
08/88-05/92 College of William & Mary, VA, B.S. (Chemistry)
Courses, Websites, Pubs
Publications
Tobias, H.J., Pitesky, M. Fergenson, D.P., Steele, P.T., Horn, J., Frank, M., Gard, E.E. ”Following the biochemical and morphological changes of Bacillus atrophaeus cells during the sporulation process using Bioaerosol Mass Spectrometry.” Journal of Microbiological Methods, 2006, 67, 56-63.
Tobias, H.J., Schafer, M.P., Pitesky, M. Fergenson, D.P., Horn, J., Frank, M., Gard, E.E. ”Bioaerosol Mass Spectrometry (BAMS) for the Rapid Detection of Individual Airborne Mycobacterium tuberculosis H37Ra Particles.” Applied and Environmental Microbiology, 2005, 71, 6086-6095.
Fergenson, D., Pitesky, M., Tobias, H.J., Steele, P.T., et. al., E.E. ”Detection and Classification of Individual Bioaerosol Particles.” Analytical Chemistry, 2004, 76, 373-378.
Tobias, H.J.; Ziemann, P.J. "Kinetics of the Gas-Phase Reactions of Alcohols, Aldehydes, Carboxylic Acids, and Water with the C13 Stabilized Criegee Intermediate formed from Ozonolysis of 1-Tetradecene." Journal of Physical Chemistry A, 2001, 105, 6129-6135.
Tobias, H.J., Beving, D.E., Ziemann, P.J., Sakurai, H., Zuk, M., McMurry, P.H., Zarling, D., Waytulonis, R., Kittelson, D.B. “Chemical Analysis of Diesel Engine Nanoparticles Using a Nano-DMA/Thermal Desorption Particle Beam Mass Spectrometer.” Environmental Science and Technology, 2001, 35, 2233-2243.
Tobias, H.J.; Kooiman, P.M.; Docherty, K.S.; Ziemann, P.J. “Real-Time Chemical Analysis of Organic Aerosols Using a Thermal Desorption Particle Beam Mass Spectrometer.” Aerosol Science and Technology, 2000, 33, 170-190.
Tobias, H.J.; Ziemann, P.J. “Compound Identification in Organic Aerosols Using Temperature-Programmed Thermal Desorption Particle Beam Mass Spectrometry.” Analytical Chemistry, 1999, 71, 3428-3435.
Tobias, H.J.; Brenna, J.T. “On-Line Pyrolysis as a Limitless Reduction Source for Isotopic Analysis of Organic Derived Hydrogen.” Analytical Chemistry, 1997, 69, 3148-3152.
Tobias, H.J.; Brenna, J.T. “High-Precision D/H Measurement from Organic Mixtures by Gas Chromatography Continuous-Flow Isotope Ratio Mass Spectrometry Using a Palladium Filter.” Analytical Chemistry, 1996, 68, 3002-3007.