Maggie, a 7-year-old female spayed Weimaraner, was presented to the Neurology Service at the Cornell University Hospital for Animals for further evaluation of progressive ataxia and cervical pain. She was a nervous dog with a low-grade heart murmur and prominent sinus arrhythmia. Maggie previously has been diagnosed by MRI with bulging discs at C5-6 and C6-7. Thoracic radiographs were within normal limits. Maggie's cervical MRI was repeated, followed the next day by a ventral slot decompression and fenestration. Because of Maggie's nervous disposition, substantial premedication was warranted prior to induction for her MRI and surgery. Before her MRI, Maggie received dexmedetomidine, butorphanol, and diazepam. She developed an irregular bradyarrhythmia after induction with propofol, which persisted after atipamezole administration. She also developed hypotension although her systolic pressure remained normal to elevated. To try to avoid profound bradycardia and arrhythmias during her surgery the next day, Maggie was premedicated with morphine and acepromazine; she was also started on a fentanyl CRI after induction for analgesia and to minimize the hypotensive effects of high dose inhalant anesthesia. Her mean arterial pressure dropped quite low although her systolic pressure again remained normal to substantially elevated throughout the procedure; Maggie was treated throughout the nearly seven hours of anesthesia with varying combinations of dopamine, glycopyrrolate, and phenylephrine, along with intravenous crystalloids and boluses of hetastarch. This paper will discuss anesthetic-related risks in Maggie's case, our anesthetic protocols for her MRI and surgery, complications that arose during her procedures, and treatments employed to alleviate those complications. Physiology related to the various anesthetic drugs used during Maggie's procedures will be reviewed.